The integration of information flow and the characteristics of information for precision pesticide application in the intelligent plant protection machinery were discussed. After analyzing the data structure conversion and integration of spatial data and temporal data, the GPS data collection and storage and the ODBC interface were studied, respectively. The visibility of GPS signals from the satellites was recorded and analyzed using a developed GPS experimental set-up. Then the comparison of GPS accuracy was conducted using different systems. The integration of meteorological databases with other sources of information for precision pesticide application, and correlation between hygro-thermal coefficients and occurrence of forest plant diseases and insects infestation were analyzed.