Soil moisture is different under different layout style of drip irrigation pipeline, which will affect crop growth and its yield. In this study, soil moisture and water physiological indexes under different treatments during grape ripeness were measured and analyzed in order to investigate the effect of layout style of pipeline and technical parameters of drip irrigation system on grape’s growth, yield and select the optimal technique parameters of drip irrigation that suitable for TuHa Basin. The results show that the treatment with three surface drip irrigation pipelines，outlet flow of 2.7 L/h and the distance of 30 cm between the emitters has the optimal results. Under the condition of this treatment, soil moisture, grape’s water physiological indexes and yield all reach a higher level.