The Three Gorges Reservoir Area (TGRA) has often suffered the most serious soil erosion in recent years. Soil erosion control still remains on the purple soil, the main soil type for the sloping farmland in this area. Among them, enzyme-induced carbonate precipitation (EICP) can rely on the urease enzymes to catalyze urea. Specifically, the urea can be decomposed into ammonium and carbonate anions, and then precipitated the calcium carbonate (CaCO₃) with the presence of carbonate anions and external calcium sources. EICP has been proven to efficiently strengthen the soil for less infiltration, in order to restore the rock and heritage. A promising approach can be regarded to effectively control soil erosion. However, the effect of EICP on the soil detachment capacity is still far from clear, especially for the response of soil detachment to the EICP concentration and maintenance time. Therefore, this study aims to clarify the effect of EICP solution concentration and maintenance duration on the soil detachment capacity of purple soil in the Three Gorges Reservoir Area. The purple soil in the TGRA was taken as the research material. The scouring experiments were conducted under five EICP solution concentrations (0 (for control check), 0.5, 1.0, 1.5, and 2.0 mol/L) at six maintenance durations (1, 7, 15, 30, 60, and 120 d), in order to estimate the soil detachment capacity. Also, the apparent cohesion and calcium carbonate content were measured at different experiment conditions. Moreover, the SEM was employed to reveal the micro-mechanism of erosion reduction by EICP. The results indicated that the soil detachment capacity of purple soil significantly decreased with the application of EICP solution. Compared with the CK, the soil detachment capacity decreased by 19.63%-86.92%, 38.79%-89.41%, 48.13%-89.91%, and 31.78%-84.49%, respectively, at the EICP solution concentration of 0.5, 1.0, 1.5 and 2.0 mol/L, with the most pronounced effect at the concentration of 1.5 mol/L. Additionally, the soil detachment capacity decreased rapidly, whereas, the subsequent slowly decreased as maintenance duration increased. Compared with the maintenance for 1 d, the decreases at 7, 15, 30, 60, and 120 d were 19.79%-84.08%, 33.81%-87.80%, 87.27%-94.21%, 91.41%-93.18%, and 91.18%-92.77%, respectively. Moreover, the reduction amplitude in the soil detachment capacity accounted for 85.79%-92.21% of the total reduction amplitude at the maintenance duration of 7 d under the application of the EICP solution. The apparent cohesion and calcium carbonate content of purple soil showed a trend of increase followed by a decrease with the increase of EICP solution concentration. Compared with the CK, the apparent cohesion increased by 43.70%-77.43%, 58.54%-101.21%, 77.06%-135.68%, and 64.08%-87.86%, respectively, at the EICP solution concentration of 0.5, 1.0, 1.5 and 2.0 mol/L, while the calcium carbonate content increased by 10.29-17.35 times, 11.12-23.00 times, 12.00-29.59 times and 10.88-24.35 times, respectively. Additionally, the apparent cohesion increased by 10.46%-36.38%, 21.98%-46.46%, 35.12%-55.41%, 45.15%-65.49%, and 48.61%-72.76%, respectively, at the maintenance for 7, 15, 30, 60 and 120 d, compared with the maintenance for 1 d. The content of calcium carbonate increased by 54.17%-133.48%, 60.94%-134.39%, 61.98%-134.84%, 61.46%-134.84%, and 62.50%-135.29%, respectively, at the maintenance for 7, 15, 30, 60 and 120 d under the application of EICP solution, compared with the stable content in the CK. The increase amplitude in the apparent cohesion and calcium carbonate content accounted for 37.59%-59.56% and 78.26%-98.66% of the total increase amplitude, respectively, at the maintenance duration of 7 d. Additionally, the microscopic analysis exposed that the soil detachment capacity was reduced to aggregate the calcium carbonate in the soil surface under the application of EICP solution. Furthermore, the soil detachment capacity was better described by the apparent cohesion and calcium carbonate content with an exponential function. The findings can provide theoretical guidance to promote erosion control in the application of EICP on soil detachment of purple soil in the TGRA.